What is a drug sensitivity test?

A drug sensitivity test is a lab test that measures how easily cells are killed by a drug. When you order a Personalized Prediction Profile, ImpriMed uses a proprietary high-throughput ex vivo drug sensitivity testing platform to analyze your patient’s live cells.

For our canine leukemia and lymphoma service, we expose the cells to 13 different drugs commonly used to treat these diseases: L-Asparaginase, Mitoxantrone, Vincristine, Vinblastine, Doxorubicin, Rabacfosadine (Tanovea®), Chlorambucil, Mechlorethamine, Lomustine, Prednisolone (activated Prednisone), Mafosfamide (activated Cyclophosphamide), Melphalan, and Dexamethasone.-

What does PARR tell me about my patient’s specimen?

PARR, which stands for PCR for Antigen Receptor Rearrangements, is used to discriminate between lymphoma/leukemia and reactive/inflammatory conditions when cytology is equivocal. Our canine PARR assay detects the expansion of B-cell cancer clones by amplifying the VJ region of the immunoglobulin heavy chain gene (IgH) and detects the expansion of T-cell cancer clones by amplifying a region in the T-cell receptor gamma chain gene.

If I send samples from multiple patients, do I get a discount?

No, but after the first Personalized Prediction Profile service for a given patient, all subsequent Personalized Prediction Profile services for that patient are discounted.

I put the media tubes into the freezer. Can I still use the media tubes?

No, We will send you another batch of media tubes you could use. Please email us at support@imprimedicine.com or request fresh tubes online via our Vet Portal.

Are shipping costs extra?

Yes, we charge next-day air (overnight shipping). As our state-of-the-art laboratory is in Palo Alto, CA, the distance a sample travels to our lab will directly influence the shipping fee applied. Please contact sales@imprimedicine.com for the precise shipping fee for your area.

What is the simulated dosing for a certain drug? MTD(maximum tolerated dosing) or metronomic?