Ex Vivo CRO services
ImpriMed partners with pharmaceutical and biotech sponsors on ex vivo drug sensitivity studies, biomarker validation, and translational research using xCellSense™ platform built on real patients.
† Turnaround time may vary depending on the project scope
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Frequently asked questions
Platform & Technology
What makes ex vivo drug sensitivity testing more predictive than cell line models?
Patient-derived primary cells retain the genetic heterogeneity, microenvironment interactions, and drug resistance mechanisms present in actual tumors. Cell lines have been passaged extensively and often lose key biological features that influence drug response. Our platform tests compounds in fresh patient samples that maintain their original immunophenotypic and genomic characteristics, providing data that more accurately predicts clinical outcomes.
How does xCellSense™ differ from other patient-derived testing platforms?
xCellSense™ is specifically optimized for hematologic malignancies with real-time live-cell functional analysis. We have developed specialized protocols for blood cancer cells that require different handling, culture conditions, and readout methods.
What quality standards does ImpriMed maintain?
ImpriMed operates two laboratories: our Silicon Valley lab, A2LA-accredited to ISO 17025 standards, and our Seoul lab, certified under KGMP and holding an IVD Medical Device Manufacturing License, ensuring quality and regulatory compliance across global projects.
Which drug modalities are supported by your platform?
Our platform accommodates diverse therapeutic modalities, including biologics with direct cytotoxic effects, small molecules, peptides, oligonucleotides, enzymes, antibody-drug conjugates, and immunomodulatory agents. For cell-based therapies and immunotherapies, we can design custom assays that incorporate relevant immune cell populations or measure immunophenotypic changes. Contact us to discuss your specific therapeutic approach.
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